The treatment for cervical cancer is comprised of surgery (including localized excision of the tumor) during early stages, and chemotherapy and radiation during the advanced stages of the disease. Types of cervical tumors: squamous cell carcinoma, which account for about 80% of the cervical tumors. This is a tumor originating in the flat cells of the inner lining of the cervix. Adenocarcinoma, which originate in the outer gland cells and are rarer.
The treatment for cervical cancer at the advanced metastasized stage is currently based on chemotherapy. However, testimonies have begun to be received recently that these tumors may respond to biological therapy or immunotherapy.
Biological therapy: biological drugs work on various receptors in cancerous tissue with the aim of preventing the cancer from proliferating or of affecting genome mutations that activate cell-division mechanisms. In this way, these targeted drugs succeed in destroying the tumor. Immunotherapy: drugs that use the immune system to fight the tumor, when the tumor is paralyzing the immune system. One of the known mechanisms uses the immune system in a focused way with drugs that inhibit PD1. Recently, testimonies have begun to be received that these tumors may respond to immunotherapy, particularly when many mutations were found in these tumors.
Personalized therapy: in instances when tumors are not responding to the customary chemotherapy, advanced tests may be used in order to try to pinpoint targets for various treatments. The most suitable therapy may then be decided according to the biological characteristics of the tumor tissue, whether chemotherapy, biological therapy, immunotherapy or even hormone therapy, which had not previously been considered effective.